Systemic Corticosteroids for Acute Exacerbations of Chronic Obstructive Pulmonary Diseases
نویسندگان
چکیده
منابع مشابه
Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease.
BACKGROUND Acute exacerbations of chronic obstructive pulmonary disease (COPD) are a major cause of hospital admission and mortality. They contribute to long-term decline in lung function, physical capacity and quality of life. The most common causes are infective, and treatment includes antibiotics, bronchodilators and systemic corticosteroids as anti-inflammatory agents. OBJECTIVES To asses...
متن کاملAntibiotics in addition to systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease.
RATIONALE The role of antibiotics in acute exacerbations is controversial and their efficacy when added to systemic corticosteroids is unknown. OBJECTIVES We conducted a randomized, placebo-controlled trial to determine the effects of doxycycline in addition to corticosteroids on clinical outcome, microbiological outcome, lung function, and systemic inflammation in patients hospitalized with ...
متن کاملOral corticosteroids for exacerbations of chronic obstructive pulmonary disease.
Background. The role of oral corticosteroids in treating patients with exacerbations of chronic obstructive pulmonary disease (COPD) remains contentious. We assessed in a prospective, randomised, doubleblind, placebo-controlled trial the effects of oral corticosteroid therapy in patients with exacerbations of COPD requiring hospital admission. Methods. We recruited patients with non-acidotic ex...
متن کاملAcute exacerbations of chronic obstructive pulmonary disease.
Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined by modification of the usual COPD symptoms, dyspnea, coughing and sputum, beyond daily variations, with a sudden onset, and requiring modification of the usual treatment. Exacerbations stud the course of COPD. Their frequency is variable, averaging 1-2 per year. Their frequency generally increases with COPD severity. ...
متن کاملAcute Exacerbations of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a disease which is characterized by airway inflammation and progressive airflow limitation with poor reversibility. Patients with COPD can experience periods of acute deterioration, which are called exacerbations. There are different definitions for an acute exacerbation of COPD (AECOPD). A symptom reported AECOPD is defined solely based on a pati...
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ژورنال
عنوان ژورنال: Academic Emergency Medicine
سال: 2020
ISSN: 1069-6563,1553-2712
DOI: 10.1111/acem.14012